Sobrevida global de mulheres com câncer de mama no estado do Espírito Santo, Brasil e seus fatores associados
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Data
2024-06-16
Autores
Pessanha, Raphael Manhães
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Universidade Federal do Espírito Santo
Resumo
Introduction: Despite significant advances in treatment, breast cancer is still responsible for many deaths, being the fifth leading cause of cancer mortality worldwide, with 685,000 deaths. In Brazil, breast cancer ranks first in all Brazilian regions, excluding non-melanoma skin tumors. Survival analysis is crucial to assess the effectiveness of available treatments and to measure the impact of health policies on patients' longevity and quality of life. Survival studies can also reveal disparities in treatment and outcomes, allowing policies to be adjusted to better meet patients' needs. Furthermore, the lack of studies focused on the survival of women with breast cancer in Espírito Santo (ES) represents an important gap. Objective: To investigate the occurrence of malignant breast neoplasms in the state of Espírito Santo; to assess the quality and completeness of data as well as the overall survival of women with breast cancer and its associated factors. Methods: Secondary data were collected via Tumor Registration Form (TRF) from the Hospital Cancer Registries (HCR) of patients who received care at a hospital in the Oncology Care Network (OCN) of ES, and from the Mortality Information System (SIM), in the period between 2000 and 2020. The cohort consisted of women over 18 years of age, who were diagnosed with breast cancer, according to ICD-10: "C50: Malignant Neoplasm of the Breast", with anatomopathological examination and being followed up at the OCN of ES. For data analysis, a descriptive analysis of the epidemiological profile of patients diagnosed with breast cancer was performed, in addition to an analysis of the completeness of the epidemiological variables of the HCR of ES, where data incompleteness was classified as excellent (50%), according to the percentage of missing information. For survival analysis, the deterministic linkage method was used, of the TRF records of the HCR Integrator with the SIM records. For the 5-year survival analysis, the Kaplan-Meier and LogRank methods were used. In addition, the Cox proportional hazard model for specific cause of death was used in the multivariate analysis. For all statistical analyses, alpha was set at 5%. Results: A total of 16,587 cases of breast cancer (BC) were recorded from 2000 to 2020. The variables alcoholism …
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Neoplasias da Mama , Registros Hospitalares de Câncer , Epidemiologia , Análise de Sobrevida , Estimativa de Kaplan-Meier , Modelos de Riscos Proporcionais