Ciências Farmacêuticas

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http://repositorio.ufes.br/handle/10/17568
Programa de Pós-Graduação em Ciências Farmacêuticas

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Navegando Ciências Farmacêuticas por Assunto "Adesão à medicação"

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    A dispensação de medicamentos influencia o conhecimento e a adesão do paciente sobre sua farmacoterapia? Uma revisão sistemática e metanálise
    (Universidade Federal do Espírito Santo, 2024-08-28) Santana, Elizabete Priscila Costa; Santos Júnior, Genival Araújo dos; Rocha, Kérilin Stancine Santos; https://orcid.org/0000-0002-2313-2140; Santos, Sabrina Cerqueira; Santana, Rafael Santos
    Background: Patient's inadequate medication knowledge and non-medication adherence are considered an issue in healthcare, as they can lead to negative outcomes, such as therapeutic failures and hospitalization. Even though drug dispensing is a service traditionally performed by pharmacists, there is still no evidence about the influence of this service in these health outcomes. Objective. To evaluate the influence of drug dispensing on the patient's medication knowledge and medication adherence. Methods: A systematic review was conducted in which search was performed in PubMed/Medline, Biblioteca Virtual da Saúde, Web of Science, Embase, Open Thesis and Google Scholar databases. Two reviewers read the titles, abstracts and complete texts according to the eligibility criteria and extracted the data from the included articles. The methodological quality was assessed through the tools provided by JBI Institute. The data was analyzed through qualitative synthesis and meta-analysis was conducted for randomized controlled trials that used the outcome of medication adherence using RStudio software version 4.3.3. Results: A total of 7.590 studies were identified on the initial search, from which 11 articles met the eligibility criteria and were included in this systematic review. The studies were published in Africa, Latin America, Asia, Europe and Australia. Most of the studies were interventional (n=7). Five of the studies evaluated the influence of drug dispensing on the patient’s medication knowledge, from which four showed that knowledge increased after dispensing. Eight studies evaluated the influence of dispensing on medication adherence and the meta-analysis showed that patients who received the dispensing were 1.19 times more likely to adhere to medications compared to those who did not receive the service. Six studies met more than 70% of the quality assessment criteria. Conclusion: This systematic review showed that dispensing increases patient’s medication knowledge and patients are more likely to adhere to their medications when they receive this service.
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    Avaliação do uso de medicamentos potencialmente inapropriados e da adesão à farmacoterapia em idosos atendidos por um plano de saúde suplementar
    (Universidade Federal do Espírito Santo, 2020-08-26) Tranhago, Camilla da Penha; Bem, Daniela Amorim Melgaço Guimarães do; https://orcid.org/0000-0001-9296-7486; http://lattes.cnpq.br/8710745257083012; http://lattes.cnpq.br/7598444789597082; Pereira, Mariana Linhares; https://orcid.org/0000-0002-3214-2789; http://lattes.cnpq.br/5451495634201582; Santos Junior, Genival Araújo dos; https://orcid.org/0000000256181846; http://lattes.cnpq.br/5917097187533724
    The association between polypharmacy, the presence of multiple comorbidities and physiological changes related to aging increases the complexity of pharmacotherapy in the elderly. In this context, some medications may be considered inappropriate for these individuals. Older health insurance users were related to the use of more drugs, which may make them even more vulnerable to the use of potentially inappropriate medications (PIM). The aim of this study was to identify the prevalence of use and the factors associated with the use of PIM by elderly people affiliated with supplementary health insurance, according to the Beers 2019 criteria. This is a cross-sectional study conducted with elderly residents in the city of Vitória-ES, from a supplementary health plan. Socioeconomic, demographic and clinical data were collected through interviews during home visits, from October 2018 to June 2019. The association between the use of PIM and independent variables was verified by univariate logistic regression with their respective confidence intervals. (CI) 95%. We interviewed 332 elderly, 237 female and 95 male, the average age was 81.5 years. A 65% prevalence of PIM use was identified. In the multiple logistic regression model, the variables associated with the use of PIM were self-medication (p = 0.004), high risk clinical profile (p = 0.022), use of psychotropic medication (p = 0.000001) and use of medicines for the musculoskeletal system (p = 0.04) and alimentary tract (p = 0.03). Practicing physical activity was associated with the use of MPI as a protection factor (p = 0.02). The prevalence of polypharmacy was 79.5%. Self-medication was identified in 44.6% of patients. The adherence assessment revealed low adherence prevalence rates ranging from 6.4 to 74.7%, depending on the assessment instrument used. The factors associated with low adherence to each instrument were: age greater than or equal to 86 years (p = 0.009) and physical activity (p = 0.011) in the BMQ; having cognitive deficit (p = 0.028) in the Morisky-Green Test; and polypharmacy (p <0.0001) in MedTake. The results of this study indicate the need for changes in the care of the elderly in supplementary health, in order to increase adherence and the safety of drug therapy, thus guaranteeing a higher quality of life for this population segment.