Mestrado em Ciências Farmacêuticas
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Navegando Mestrado em Ciências Farmacêuticas por Autor "Araújo, Dyego Carlos Souza Anacleto de"
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- ItemAvaliação do conhecimento de farmacêuticos e estudantes de farmácia sobre o transtorno do espectro autista no Brasil(Universidade Federal do Espírito Santo, 2024-04-05) Rosa, Larissa Couto; Araújo, Dyego Carlos Souza Anacleto de; https://orcid.org/0000-0001-6631-465X; http://lattes.cnpq.br/5120426619544250; Santos Júnior, Genival Araújo dos; https://orcid.org/0000-0002-5618-1846; http://lattes.cnpq.br/5917097187533724; http://lattes.cnpq.br/2475269525071153; Rocha, Kérilin Stancine Santos; https://orcid.org/0000-0002-2313-2140; http://lattes.cnpq.br/4216594263272412; Silva, Rafaella de Oliveira Santos; http://lattes.cnpq.br/4008596465243842Pharmacy students’ and pharmacists’ limited knowledge about Autism Spectrum Disorder (ASD) can have negative impacts on health care for these individuals. In Brazil, there are no studies that assess the knowledge of Pharmacy students and pharmacists about ASD. Therefore, the objective of this study is to assess the knowledge of Pharmacy students and pharmacists about ASD in Brazil. A cross-sectional survey study was conducted between September 2021 and August 2022. Pharmacy students and pharmacists from all five regions of Brazil participated in the survey. Data were collected through an online questionnaire that contained two sections: the first addressed sociodemographic data and contact with people with ASD and the second section contained the items that make up the Autism Stigma Knowledge – Questionnaire (ASK-Q) Brazil. This questionnaire assesses knowledge and stigma about ASD in 49 questions divided into 4 subscales. The instrument considers the following scores for adequate knowledge: diagnosis (11-18 points); etiology (11-16 points); treatment (10-14 points); non-endorsement of stigma (3-7 points). Descriptive statistics, t test to compare mean scores, and Mann-Whitney test to compare unpaired samples were used for statistical analyses. This study was approved by the Research Ethics Committee (Opinion No. 4,464,411). A total of 397 pharmacy students and 413 pharmacists participated in the study. Most students had adequate knowledge in the following domains: etiology (99.0%), diagnosis (97.0%), and treatment (98.7%), and no student demonstrated endorsement of stigma (100.0%). The highest rates of correct answers in the total score were observed among students from public institutions (p=0.001; d=0.5). In the treatment domain, the highest scores were observed among students who had a family member with ASD (p=0.001; d=0.45) and who studied in public institutions (p=0.002; d=0.43). In the diagnosis domain, the highest scores were observed among those who had a family member with ASD (p=0.015; d=0.24) and lived with a person with ASD (p=0.007; d=0.3). Most pharmacists presented adequate knowledge in the domains: etiology (99.0%), diagnosis (99.0%), treatment (98.8%), and no pharmacist demonstrated to endorse stigma (100.0%). In the diagnosis domain, the highest scores were observed among pharmacists who reported having a family member with ASD (p<0.001) and living with a person with ASD (p=0.002). In the etiology domain, the highest scores were among people who lived with a person with ASD (p=0.004). This study revealed that the pharmacists and pharmacy students analyzed had adequate knowledge about ASD. The results may contribute to the development of strategies that improve the continuing education of Brazilian pharmacists.
- ItemQuais fatores influenciam o envolvimento de pacientes, familiares e/ou cuidadores na segurança do uso de medicamentos no hospital? Uma revisão de escopo(Universidade Federal do Espírito Santo, 2025-02-21) Martins, Bruna Lanes; Araújo, Dyego Carlos Souza Anacleto de; https://orcid.org/0000-0001-6631-465X; http://lattes.cnpq.br/5120426619544250; Silvestre, Carina Carvalho; https://orcid.org/0000-0002-2162-0810; http://lattes.cnpq.br/1791505264817019; https://orcid.org/0009-0006-4479-2750; http://lattes.cnpq.br/4305360735331504; Nascimento, Mariana Martins Gonzaga do; https://orcid.org/0000-0003-2183-4365; http://lattes.cnpq.br/4157162836464120; Varallo, Fabiana Rossi; https://orcid.org/0000-0003-4016-1442; http://lattes.cnpq.br/8242821398408335Introduction: The involvement of patients, family members, and/or caregivers in the medication use process is a crucial strategy for promoting safety and optimizing health outcomes. However, there is a gap in the literature regarding a comprehensive synthesis of the factors influencing this involvement. Objective: To synthesize the factors that influence patient and family involvement in medication safety in the hospital setting. Methods: A scoping review was conducted following the methodology proposed by the Joanna Briggs Institute. Searches were performed in January 2024 in the Medline (via PubMed), LILACS, Embase, and Web of Science databases, as well as in gray literature, including dissertations and technical reports. Two independent reviewers screened titles, abstracts, and full texts, extracting data based on pre-established criteria. The identified factors were categorized into categories and subcategories. Results: A total of 1,483 records were identified, of which 17 met the inclusion criteria. These studies were conducted in various countries, with Australia (n=4) and England (n=4) being the most represented. Patient perceptions of their involvement were assessed in all studies (n=17), while the perspectives of nurses (n=7), physicians (n=4), and pharmacists (n=3) were also explored. In total, 31 factors were identified and organized into four categories: patient-related (e.g., health literacy, confidence, interest; n=15), family or caregiver-related (e.g., caregiving role, prior experience; n=3), healthcare professional-related (e.g., communication, workload; n=7), and environment-related (e.g., noise, safety culture; n=6). Additionally, the studies highlighted barriers and facilitators influencing engagement, such as time constraints for healthcare professionals, fear of legal repercussions, and a lack of role clarity in the hospital setting. Conclusion: The factors influencing the involvement of hospitalized patients and their families in medication safety behaviors are broad and multifaceted. While some factors act as barriers, others facilitate engagement. These findings provide insights for developing strategies and policies aimed at enhancing patient safety in hospitals, with potential applicability to other healthcare settings.
- ItemTranstornos mentais comuns e uso de medicamentos psicotrópicos entre professores da rede estadual de ensino do Espírito Santo(Universidade Federal do Espírito Santo, 2025-04-01) Mazzini, Yohan Cancilheri; Araújo, Dyego Carlos Souza Anacleto de; https://orcid.org/0000-0001-6631-465X; http://lattes.cnpq.br/5120426619544250; Ângelo, Vitor Amorim de; Aguiar, Patrícia MeloIntroduction: Common mental disorders and the use of psychotropic medications among teachers have become an issue of growing global concern. However, in Brazil, there is a lack of probabilistic studies with representative samples investigating the prevalence of anxiety and depression symptoms, as well as the use of psychotropic drugs in this specific population, limiting the understanding of the true magnitude of the problem. Objective: To assess the prevalence and associated factors of common mental disorder symptoms and psychotropic medication use among public school teachers in Espírito Santo. Method: A cross-sectional, quantitative study was conducted with teachers from schools linked to the Carnapian Regional Education Superintendency (SER-Carapina). Teachers who were assigned to non-teaching roles were excluded. Cluster sampling was carried out, considering each school as a primary sampling unit. Data collection was conducted in person between January and February 2024, during the Pedagogical Planning Sessions in the randomly selected schools. Semi-structured questionnaires were applied, including questions on sociodemographic data, previous diagnosis of mental disorders, screening scales for anxiety, depression, insomnia, and burnout symptoms, as well as the profile of psychotropic medication use. Statistical analysis included descriptive statistics, chi-square tests, Poisson regression with robust variance, and binary logistic regression. The study was approved by the Research Ethics Committee (CAAE: 70203023.4.0000.5060). Results: A total of 453 teachers participated in the study. A previous diagnosis of anxiety and depression disorders was reported by 29.6% (n=134) and 14.8% (n=67) of teachers, respectively. Moderate to severe symptoms of anxiety and depression were observed in 32.7% (n=148) and 34.4% (n=156) of teachers. Additionally, 11.3% (n=51) presented suicidal or self-harm ideation with some frequency. Poisson regression indicated that being a woman, having another job besides teaching, and having clinical insomnia and burnout increased the prevalence ratio of anxiety symptoms, while being a woman, having clinical insomnia, and burnout increased the prevalence ratio of depression symptoms. The use of psychotropic medications was reported by 20.0% (n=90) of teachers, with the specific use of antidepressants observed in 16.9% (n=76). Most teachers began using these medications after 2020, with prescriptions primarily issued by psychiatrists. Poisson regression showed that being a woman, having clinical insomnia, and experiencing severe anxiety symptoms increased the prevalence ratio of psychotropic and antidepressant use. The use of benzodiazepines was reported by 6.8% (n=31) of teachers. Among users, 42.5% (n=14) had been using these medications for 2 to 5 years, and 39.4% (n=13) reported benzodiazepine use without an associated antidepressant. Binary logistic regression showed that severe anxiety symptoms and clinical insomnia increased the likelihood of benzodiazepine use, while having a partner reduced these chances. Conclusion: Teachers in Espírito Santo exhibited higher prevalence rates of common mental disorders compared to national and global population averages. The use of psychotropic medications, particularly antidepressants and benzodiazepines, was also higher than in other populations, highlighting the need for public policies aimed at workers’ health. These data highlight the need to implement multidimensional strategies that integrate individual actions, institutional support that includes modifying stressors, and robust public policies aimed at preventing mental illness and promoting the health of teachers.