Mestrado em Biotecnologia

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http://repositorio.ufes.br/handle/10/17567

Nível: Mestrado Acadêmico
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    BUSCA DE BIOMARCADORES DE LONGEVIDADE HUMANA: INVESTIGAÇÃO DO GENE IPMK
    (Universidade Federal do Espírito Santo, 2023-08-28) Marin, Gabriela do Nascimento; Paula, Flavia de; https://orcid.org/0000000186792982; http://lattes.cnpq.br/7913201450663683; https://orcid.org/; http://lattes.cnpq.br/; Naslavsky, Michel Satya; https://orcid.org/; http://lattes.cnpq.br/; Sena, Geralda Gillian Silva; https://orcid.org/; http://lattes.cnpq.br/; Errera, Flavia Imbroisi Valle; https://orcid.org/; http://lattes.cnpq.br/9337327437538048
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    AVALIAÇÃO EPIGENÉTICA DO GENE BDNF E A RELAÇÃO COM A INSEGURANÇA ALIMENTAR E NUTRICIONAL EM USUÁRIOS DO SUS
    (Universidade Federal do Espírito Santo, 2023-08-15) Luz, Thaiany Marcelino; Silva, Adriana Madeira Alvares da; https://orcid.org/0000000280780304; http://lattes.cnpq.br/6445492335035108; https://orcid.org/; http://lattes.cnpq.br/; Barbosa, Wagner Miranda; https://orcid.org/; http://lattes.cnpq.br/; Arantes, Lidia Maria Rebolho Batista; https://orcid.org/; http://lattes.cnpq.br/
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    Avaliação da citotoxicidade de biomaterial ósseo descelularizado
    (Universidade Federal do Espírito Santo, 2023-04-14) Favalessa, Affonso Martinho Burini Bortolotti; Nogueira, Breno Valentim; https://orcid.org/0000000221990635; http://lattes.cnpq.br/0011229320439147; https://orcid.org/; http://lattes.cnpq.br/9081245259555507; Maranduba, Carlos Magno da Costa; https://orcid.org/0000-0001-7327-1934; http://lattes.cnpq.br/4763153859701731; Paula, Flavia de; https://orcid.org/0000000186792982; http://lattes.cnpq.br/7913201450663683
    The regeneration of bone defects of different origins is still a challenge in the medical and dental fields. Currently, numerous bone substitutes are used in grafting procedures resulting from injuries or trauma. However, only a few manage to promote biochemical interactions with the body, being the targets of research in bone tissue regeneration. Therefore, tissue bioengineering is responsible for evaluating the capacity for osseointegration, a direct interaction between the bone and the implanted biomaterial, which promotes rapid adhesion and higher quality in the procedure. Results of previous research from the Tissue Biotechnology Center have shown to produce a decellularized scaffold from fetal bone tissue with morphological characteristics ideal to be a new and promising bone biomaterial. Continuing the research, this project aims to evaluate the cytotoxicity of the biomaterial when in contact with mesenchymal stem cells (MSC). The decellularization of fetal bone biomaterial of bovine origin was performed and then the value of residual DNA and SDS, elemental composition and cytotoxicity test with human cells derived from adipose tissue stromal mesenchyme were analyzed. Finally, this study evaluated the bone scaffolds developed in this study showed low biocompatibility in vitro, demonstrating the low adhesion of the cells to the material.
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    DESENVOLVIMENTO DE HIDROGEL DERIVADO DE OSSO BOVINO FETAL ENRIQUECIDO COM PLASMA RICO EM PLAQUETAS
    (Universidade Federal do Espírito Santo, 2023-04-05) Colombeki, Fernanda Mendes; Nogueira, Breno Valentim; https://orcid.org/0000000221990635; http://lattes.cnpq.br/0011229320439147; https://orcid.org/; http://lattes.cnpq.br/; Maranduba, Carlos Magno da Costa; https://orcid.org/; http://lattes.cnpq.br/; Paula, Flavia de; https://orcid.org/0000000186792982; http://lattes.cnpq.br/7913201450663683
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    DESENVOLVIMENTO DE HIDROGEL DERIVADO DE MATRIZ EXTRACELULAR ÓSSEA BOVINA ADULTA E FETAL
    (Universidade Federal do Espírito Santo, 2023-03-20) Rabello, Thais Leal; Nogueira, Breno Valentim; https://orcid.org/0000000221990635; http://lattes.cnpq.br/0011229320439147; https://orcid.org/; http://lattes.cnpq.br/; Maranduba, Carlos Magno da Costa; https://orcid.org/; http://lattes.cnpq.br/; Paula, Flavia de; https://orcid.org/0000000186792982; http://lattes.cnpq.br/7913201450663683
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