Ciências Odontológicas

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Navegando Ciências Odontológicas por Assunto "Adenoma pleomórfico"

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    Perfil histopatológico e demográfico das neoplasias de glândulas salivares em um centro universitário de referência para diagnóstico no estado do Espírito Santo
    (Universidade Federal do Espírito Santo, 2025-01-25) Santos, Tainã Figueiredo; Barroso, Danielle Resende Camisasca; https://orcid.org/0000-0003-1193-2113; http://lattes.cnpq.br/3989074593181674; Barros, Liliana Aparecida Pimenta de; Pereira, Fausto Edmundo Lima
    To describe the incidence and compare the clinical-pathological characteristics of pleomorphic adenoma (PA) of minor and major salivary glands. A cross-sectional, observational, descriptive study was carried out, collecting sociodemographic and clinical-pathological data from all cases of PA of salivary glands at a referral center for oral lesions (SAP Bucal-UFES) and a university hospital (HUCAM/EBSERH-UFES), between 2004-2022. The information was obtained from histopathological request forms and patient records. The association between the variables was verified by Pearson's chi-square test and multivariate logistic regression analysis. Seventeen primary PA of minor salivary glands were identified, with 3 more recurrences, and 33 primary PA of major salivary glands. Of the total cases of PA of minor salivary glands, 14 cases were found in females and 19 cases in the majors. The mean age was higher in patients with PA of the major salivary glands (42.3 years) compared to the minor ones (38.9 years) (p = 0.08). PA of the major salivary gland was more prevalent (n = 33), while minor PA tended to present recurrences (n = 3). Logistic regression revealed that partial capsular coverage was more prevalent in PA of the minor salivary glands (OR = 0.056; 95% CI: 0.005–0.607; p = 0.018), reflecting a potentially high risk of recurrence. In histopathological terms, PA of the major salivary glands showed a higher cell frequency, due to the higher frequency of cellular islands (OR: 0.082; 95% CI: 0.007–0.959; p = 0.046), demonstrating greater cellular supply and greater capacity for complete capsular production. Given the above, the variables, age, capsule completeness, presence of islands or cellularity and lesion size, distinguished AP from minor salivary glands from major ones