Mestrado em Nutrição e Saúde

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    Adiposidade abdominal e sua relação com consumo alimentar, estresse e qualidade de vida de profissionais de segurança pública
    (Universidade Federal do Espírito Santo, 2024-04-10) Silva Neto, Luiz Claudio Barreto; Co-orientador1; https://orcid.org/; http://lattes.cnpq.br/; Co-orientador2; https://orcid.org/; http://lattes.cnpq.br/; Co-orientador3; https://orcid.org/; http://lattes.cnpq.br/; Co-orientador4; ID do co-orientador4; Lattes do co-orientador4; Orientador1; https://orcid.org/; http://lattes.cnpq.br/; Orientador2; https://orcid.org/; http://lattes.cnpq.br/; https://orcid.org/; http://lattes.cnpq.br/; 1º membro da banca; https://orcid.org/; http://lattes.cnpq.br/; 2º membro da banca; https://orcid.org/; http://lattes.cnpq.br/; 3º membro da banca; https://orcid.org/; http://lattes.cnpq.br/; 4º membro da banca; http://lattes.cnpq.br/; 5º membro da banca; https://orcid.org/; http://lattes.cnpq.br/; 6º membro da banca; https://orcid.org/; http://lattes.cnpq.br/; 7º membro da banca; https://orcid.org/; http://lattes.cnpq.br/
    Abdominal adiposity is a public health challenge that affects public safety personnel exposed to high levels of stress. This complex interaction between psychological and social factors can trigger adverse responses in the body, with a significant impact on quality of life. The main objective of this study was to evaluate abdominal adiposity and investigate its association with food consumption, stress levels, biochemical variables as well as quality of life in public security agents. This is a cross-sectional study carried out with 216 public safety personnel in the state of Espírito Santo. To assess symptoms of stress, food consumption and quality of life, the Stress Symptom Inventory (ISSL), the Food Consumption Frequency Questionnaire (QFCA) and the WHOQOL-bref were used, respectively. Statistical analyzes included chi-square tests, Mann Whitney tests, Poisson regression and multiple regression models (95% CI). There was a prevalence of overweight among public safety personnel (67.8%). It was observed that agents with a higher body mass index (BMI) had an increased prevalence of abdominal adiposity, indicating a significant association between these variables (PR: 3,35 [IC95%: 3,4-5,52; p=0,001]). Furthermore, those with greater adherence to the consumption of ultra-processed foods also showed a higher prevalence of abdominal adiposity(PR: 1,68 [IC95%: 1,51- 2,47] p=0,007. Stress symptoms were associated with a 64% increase in the risk of greater abdominal adiposity, while greater adherence to ultra-processed foods demonstrated a 10% increase in the risk of abdominal adiposity. These results highlight a bidirectional relationship between stress and abdominal adiposity, highlighting the importance of stress and the consumption of ultra processed foods in increasing the risk of abdominal adiposity. Such factors can have metabolic and systemic impacts, resulting in a deterioration in the quality of life of these professionals, highlighting the urgency of interventions in this population
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    Doença mineral e óssea da doença renal crônica, estado nutricional e fatores associados : estudo em indivíduos em hemodiálise da Região Metropolitana da Grande Vitória
    (Universidade Federal do Espírito Santo, 2024-06-21) Péterle, Fernanda Zobole; Salaroli, Luciane Bresciani ; https://orcid.org/0000-0002-1881-0306 ; http://lattes.cnpq.br/3503255904138561 ; https://orcid.org/0000-0002-4912-0391 ; http://lattes.cnpq.br/4452451505848265 ; Vieira, Tamires dos Santos; https://orcid.org/0000-0002-3899-3664 ; http://lattes.cnpq.br/9014510901567961 ; Paixão, Mírian Patrícia Castro Pereira ; https://orcid.org/0000-0001-5537-4323 ; http://lattes.cnpq.br/9001805537017932
    Chronic kidney disease is closely related to Chronic Kidney Disease-Mineral and Bone Disorder, resulting in distinct nutritional contexts. This study aimed to evaluate the laboratory constituents of Chronic Kidney Disease-Mineral and Bone Disorder, along with clinical, sociodemographic, and nutritional factors in hemodialysis patients in the Greater Vitória Metropolitan Region. This cross-sectional study included 790 hemodialysis patients (58% men) with a mean age of 54.23 years. Chronic Kidney Disease-Mineral and Bone Disorder was assessed using specific diagnostic criteria. Sociodemographic tools, lifestyle habits, clinical characteristics, anthropometric measures, and other laboratory variables were utilized. The odds of individuals having altered ionized calcium increased in the absence of employment (OR:1.50) and with an income below the minimum wage (OR:2.00). Alcoholism (OR:1.40) and a significantly increased waist circumference (OR:3.04) increased the chances of altered vitamin D levels. Elderly individuals (OR:2.04) showed a higher chance of altered phosphorus levels. Being male (OR:0.61), having higher education (OR:0.84), and maintaining the thickness of the adductor pollicis muscle (OR:0.58) reduced the chances of altered phosphorus levels. Black individuals (OR:0.54) showed lower chances of altered parathyroid hormone levels, while those with higher interdialytic weight gain (OR:1.01) showed higher chances of altered parathyroid hormone levels.
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    Efeitos das Mudanças na Composição Corporal e na Concentração Sanguínea de Adipocinas na Redução do Risco Cardiometabólico Após a Cirurgia Bariátrica
    (Universidade Federal do Espírito Santo, 2024-02-27) Fiorotti, Amanda Machado; Haraguchi, Fabiano Kenji; https://orcid.org/0000-0002-1019-8888; http://lattes.cnpq.br/7280084109670510; Lopes, Andressa Bolsoni; https://orcid.org/0000-0003-1244-5667; http://lattes.cnpq.br/0097480808041638; https://orcid.org/0009-0005-5599-5767; http://lattes.cnpq.br/6616433888891663; Nunes, Karolini Zuqui; https://orcid.org/0000-0003-3433-4925; http://lattes.cnpq.br/6888896554912256; Torres-Leal, Francisco Leonardo; https://orcid.org/0000-0003-4325-7458; http://lattes.cnpq.br/7925244568222989
    The remission of obesity-related diseases following bariatric surgery appears to result from the reorganization of metabolic and hormonal pathways involving adipokines. This study aimed to investigate the relationship between changes in body adiposity and serum adipokine levels, as well as the association between variations in adiponectin or resistin levels and cardiometabolic risk blood biomarkers before and after Roux-en-Y gastric bypass. A longitudinal and prospective study was conducted with bariatric surgery patients. Anthropometric, body composition and blood biochemical parameters were measured before and at 2 and 6 months post-surgery. The data were analyzed using ANOVA, Pearson or Spearman correlation, and simple linear regression with a significance level of p < 0.05. Among 36 mostly female patients aged 30 to 39 years, significant reductions in body weight (−26.8%), fat mass (−50%), waist circumference (−18%) and waist-to-height ratio (−22%) were observed post-surgery. Serum adiponectin levels increased (+107%), while resistin (−12.2%), TNF-α (−35%), and PAI-1 (−11.1%) decreased. Glucose, insulin, CRP, cholesterol, LDL-c, triglycerides, and vitamin D also decreased. Waist circumference variation showed a positive correlation with PAI-1 and TNF-α and a negative correlation with adiponectin. The total fat mass showed a positive correlation with PAI-1. Adiponectin variation correlated negatively with glucose, resistin, and CRP but positively with HDL-c. Resistin showed a positive correlation with insulin and CRP. In conclusion, 6 months post-bariatric surgery, reducing abdominal adiposity had a more significant impact on serum adipokine levels than total fat mass. Adiponectin increase and resistin decrease acted as endocrine mediators driving the remission of cardiometabolic risk biomarkers in individuals with obesity following Roux-en-Y gastric bypass.
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    Análise de métodos diagnósticos para rastreio da sarcopenia e adiposidade abdominal em mulheres com câncer de mama não metastáticos
    (Universidade Federal do Espírito Santo, 2023-09-20) Souza, Vanusa Felicio de; Guandalini, Valdete Regina; https://orcid.org/0000000322666113; http://lattes.cnpq.br/7931552401781397; https://orcid.org/; http://lattes.cnpq.br/; Junior, Luis Carlos Lopes; https://orcid.org/; http://lattes.cnpq.br/5919501773501977; Rossoni, Carina; https://orcid.org/; http://lattes.cnpq.br/
    abstract
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    Associações entre consumo alimentar, saúde óssea e composição corporal: uma análise transversal em mulheres na pós-menopausa
    (Universidade Federal do Espírito Santo, 2023-09-11) Vidigal, Camila Vilarinho; Guandalini, Valdete Regina; https://orcid.org/0000000322666113; http://lattes.cnpq.br/7931552401781397; https://orcid.org/0000-0003-4229-7968; http://lattes.cnpq.br/4660066204973582; Campos, Glaucia Cristina de; http://lattes.cnpq.br/1820731874396212; Faria, Carolina Perim de; https://orcid.org/0000-0001-9165-1332; http://lattes.cnpq.br/5520843899835735
    Menopause confirms the end of female reproductive life and is characterized by important hormonal changes. These hormonal alterations contribute to the increase and redistribution of body fat and to the loss of bone and muscle mass, which favors the development of diseases such as obesity, osteoporosis and sarcopenia. Furthermore, the simultaneous presence of these conditions can be observed, although their prevalence in the postmenopausal population is still unknown. Habits and lifestyle related to food intake, physical activity, alcohol consumption and smoking are also related to the development of obesity, osteoporosis and sarcopenia. This study had two main objectives: 1. To investigate the relationship between food intake and body composition with bone microarchitecture in postmenopausal women. 2. To verify the prevalence of osteopenic obesity and associated factors in postmenopausal women. This is a cross-sectional study, carried out between June 2019 and March 2020, with postmenopausal women for at least 12 months and aged 50 years or older, treated at the climacteric and osteoporosis outpatient clinic of a university hospital. Sociodemographic, lifestyle, clinical conditions and food intake information were collected through the application of questionnaires. An anthropometric and biochemical evaluation was performed. Body composition and bone mineral density (BMD) were analysed by dual-energy X-ray absorptiometry (DXA). The body composition variables evaluated were: percentage of body fat (BF) (%), fat mass index (FMI) (kg/m²), abdominal visceral fat (AVF) (cm²) and appendicular skeletal muscle mass index (ASMI) (kg/m²). The trabecular bone score (TBS) was used to indirectly assess bone microarchitecture. Osteopenic obesity was diagnosed considering waist circumference (WC) and BMD. Tests were applied to compare exposure variables and covariates between the categories of the outcome variable bone microarchitecture (article 1) and osteopenic obesity (article 2). Adjusted binary logistic regression analyses in 3 models were conducted to verify the association between the study exposure variables, bone microarchitecture and osteopenic obesity. A significance level of 5% was considered for all tests. The evaluated women were mostly elderly, without a partner, black/brown, with low education, did not use alcoholic beverages, non smokers, were sufficiently active, used calcium and vitamin D supplementation and did not use drugs that alter bone metabolism. Partially degraded/degraded bone microarchitecture was positively associated with body mass (OR 1.19 [CI95% 1.05 – 1.36]) (p = 0.007) and inversely associated with BF% (OR 0 .72 [CI95% 0.57 – 0.91]) (p = 0.005), ASMI (OR 0.24 [CI95% 0.07 – 0.80]) (p = 0.021) and animal protein (OR 0.86 [CI95% 0.75 – 0.98]) (p = 0.024) and magnesium intake (OR 0.96 [CI95 % 0.93 – 0.99]) (p = 0.020). A prevalence of 47.1% of osteopenic obesity was identified in the evaluated women. The presence of osteopenic obesity was positively associated with C-reactive protein (CRP) levels (OR 1.21 [CI95% 1.01 – 1.43] p = 0.035). Women with lower rates of AVF (OR 0.96 [CI95% 0.93 – 0.99] p = 0.006) and ASMI (OR 0.11 [CI95% 0.01 – 0.83] p = 0.032) were less likely to have osteopenic obesity, and those with lower protein intake (OR 1.07 [CI95% 1.02 – 1.13] p = 0.009) were more likely to have this condition. In summary, the comprehensive analysis of bone health, considering parameters such as body mass, BF%, IMMEA and animal protein and magnesium intake, emerges as a fundamental approach to evaluate bone microarchitecture. Furthermore, the high incidence of osteopenic obesity in postmenopausal women emphasizes the need for early identification and attention to factors such as AVF, ASMI, CRP and protein intake.