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A FORMAÇÃO CONTINUADA DO(A) PROFESSOR(A) DA EDUCAÇÃO INFANTIL NAS TESES E DISSERTAÇÕES DO PROGRAMA DE PÓS-GRADUAÇÃO EM EDUCAÇÃO DA UNIVERSIDADE FEDERAL DO ESPÍRITO SANTO
(Universidade Federal do Espírito Santo, 2021-12-27) Silva, Giovana Barbosa da; Foerste, Erineu; https://orcid.org/0000000328460298; http://lattes.cnpq.br/3294719644172070; https://orcid.org/0000000172172862; http://lattes.cnpq.br/6097396238094507; Ulrich, Claudete Beise; https://orcid.org/0000-0002-9830-3768; http://lattes.cnpq.br/9944681145159594; Côco, Valdete; https://orcid.org/0000-0002-5027-1306; http://lattes.cnpq.br/7335579662236147; Sodré, Liana Goncalves Pontes; https://orcid.org/0000-0001-8599-1365; http://lattes.cnpq.br/1446145510500499; Araújo, Vania Carvalho de; http://orcid.org/0000-0002-7678-1689; http://lattes.cnpq.br/4422269305808605
This research was developed through a survey of nine academic productions carried out within the scope of the Stricto Sensu Post-Graduation: theses and dissertations, defended in the Post-Graduate Program in Education of the Federal University of Espírito Santo (PPGE/Ufes), between the years from 2006 to 2017 and which thematized the Continuing Education of Early Childhood Teachers; aims to investigate how training movements, elaborated through the interaction between the object of such research and praxis (FREIRE, 2017) of Early Childhood Education teachers. In addition, it relies on the critical theory approach on the researcher/reflective teacher (STENHOUSE, 1975; SHÖN, 2000; PIMENTA and GHEDIN, 2002) in order to elucidate this doctoral dissertation on the question: which academic-scientific research contributions make possible the praxis of teachers which corroborate the affirmation of the intellectual teacher (GRAMSCI, 1989; GIROUX 1997) of Early Childhood Education? Thus, we projected the composition of this work as a qualitative approach at an exploratory bibliographic level in the collection of data (analytical corpus) that are interpreted through hermeneutics (GADAMER, 1997; GHEDIN, 2008) and also through the use of research of the research to support the construction of a paradigmatic scheme (GAMBOA; 2007,2013) as a methodological and analytical tool. Drawing on these assumptions, we list analytical categories I (The history of training movements) and II (A paradigmatic scheme for each research of the analytical corpus/PPGE-Ufes) order to make visible the constitutive aspects of educational research, as well as the means by which the interactions between the praxis of teachers and scientific productions can persist when given by " finalized”. The overall conclusion is that stricto sensu research in the Continuing Education of Early Childhood Education teachers is extremely relevant.
A formação do relacionamento fraterno entre irmãos biológicos e adotivos: uma análise sob a ótica da teoria bioecológica
(Universidade Federal do Espírito Santo, 2019-08-29) Nascimento, Danielly Bart do; Rosa, Edinete Maria; https://orcid.org/0000-0003-4279-8308; http://lattes.cnpq.br/8986579157260973; https://orcid.org/; http://lattes.cnpq.br/5882973788899245; Trindade, Zeidi Araujo; https://orcid.org/0000000305495092; http://lattes.cnpq.br/7057133930657550; Aranzedo, Alexandre Cardoso; https://orcid.org/0009-0003-4358-8414; http://lattes.cnpq.br/0831673580817928; Vargas, Elisa Avellar Mercon de; https://orcid.org/0000-0003-1229-3122; http://lattes.cnpq.br/7770917772400703; Moura, Gabriella Garcia; http://lattes.cnpq.br/1207482802921000
The thesis aims at analyzing the experience of fraternal-relationship development between biological and adopted children. In order to achieve that, two studies are reported. In the first one, the participants were members of four families who experienced the adoption of one or more children or adolescents having already one or more biological children born from the same father and mother before the adoption process. It was a longitudinal study, and it monitored the families throughout the course of one year. We used as sources for data collection semi-structured interviews with parents, children and teenagers. The semistructured interviews were conducted every three months so as to follow the process of fraternal-relationship development. A genogram was also used as an instrument allowing to investigate how participants perceived the interpersonal relations between the Family members both at the beginning and end of data collection. The second study involved four adults who experienced adoption in a family with biological children, and six adult biological children who experienced the adoption of a sibling in childhood or adolescence. Data collection was conducted through narrative interviews, which explored the participants’ life story from the moment of adoption to present moment. Data was then treated through phenomenological analysis in both studies, which allowed the construction of narratives for data presentation. The research was interested in the development of fraternal relationships based on the participants' perception, as there were no previous hypotheses. The main theory used in discussions was the Bioecological Theory of Human Development (BTHD), which was adequate for a broad understanding of the phenomenon. According to BTHD, the development of any relation requires the occurrence of interactions called proximal processes. Therefore, we sought to understand how people and the context around them influenced the emergence and maintenance of proximal processes over time. The discussion of data revealed that personal characteristics of dispositions and resources are necessary, and they need to be directed towards the engagement in joint activities between siblings. Such activities should take place over a long period of time and be favored by a context in which there is positive parental intervention in fraternal relationships. These conditions seem to favor a positive fraternal relationship. When this is not yet possible in childhood or adolescence, adulthood maturity may be an updating factor capable of allowing proximal processes to approach siblings. However, when mutual positive perceptions is formed from infancy, the relationships seem to be stronger and lasting in adulthood
ADAPTAÇÃO TRANSCULTURAL DO ADVERSE CHILDHOOD EXPERIENCES INTERNATIONAL QUESTIONNAIRE (ACE-IQ) DA ORGANIZAÇÃO MUNDIAL DA SAÚDE
(Universidade Federal do Espírito Santo, 2021-02-05) Pereira, Flávia Garcia; Viana, Maria Carmen; https://orcid.org/0000-0002-0464-4845; http://lattes.cnpq.br/4338126917250074; https://orcid.org/0000-0003-0197-511X; http://lattes.cnpq.br/6941353619549683; Miranda, Angelica Espinosa Barbosa; https://orcid.org/0000-0002-5556-8379; http://lattes.cnpq.br/5842271060162462; Barreto, Sandhi Maria; https://orcid.org/0000-0001-7383-7811; http://lattes.cnpq.br/4454863839030427; Reichenheim, Michael Eduardo; https://orcid.org/0000-0001-7232-6745; http://lattes.cnpq.br/5771380219935512; Andrade, Maria Angélica Carvalho; https://orcid.org/0000000236906416; http://lattes.cnpq.br/5427520110626795
Introduction: Adverse Childhood Experiences have often been reported in several sociodemographic and cultural contexts. However, the divergence among the methods used to evaluate these experiences has made it difficult to compare data among countries. In order to standardize its assessment and to facilitate strategies for prevention and management, the World Health Organization and the Center for Disease Control and Prevention developed the instrument named “Adverse Childhood Experiences International Questionnaire”. Objectives: 1) To identify, through an review of the literature, the instruments commonly used in the assessment of childhood adverse experiences in epidemiological research conducted over the past ten years and to compar their characteristics. 2) To produce a Portuguese-Brazilian version of the Adverse Childhood Experiences International Questionnaire, through the process of semantic equivalence. Methods: To identify scientific articles, esarches were performed in the Latin American and Caribbean Health Sciences Information System and the Medical Literature Analysis and Retrieval System Online. The Health Sciences Descriptors used, combined with Boolean operators, were: “child neglect OR life change events OR child abuse, adult survivors OR adult survivors of child abuse OR adult survivors of childhood trauma OR adult survivors, child abuse AND questionnaire”. The semantic equivalence of the instrument was performed in five phases: 1) obtaining two forward translations of the original instrument into Brazilian Portuguese and developing a combined version; 2) obtaining two retranslations of the combined version into English; 3) evaluation of the instrument items by a committee of experts, concerning: correspondence of the translation with the original version, relevance/importance, clarity, vocabulary, objectivity, applicability to the Brazilian context and regarding the instructional sequencing of the items; 4) preparation of a synthesis version of the retranslations and the first version of the Portuguese-Brazilian questionnaire; 5) performing two pre-tests to assess acceptability, understanding and emotional impact through face-to-face interviews, and obtaining the final version of the adapted questionnaire. Results: 1) Thirty-eight instruments were identified in the 253 scientific articles analyzed. The most commonly used instruments were described: Childhood Trauma Questionnaire, Childhood Experience of Care and Abuse, Adverse Childhood Experiences Questionnaire, Child Abuse and Trauma Scale, Early Trauma 9 Inventory Self Report, and Adverse Childhood Experiences International Questionnaire. The instruments analyzed differed regarding psychometric properties, age for application, and number of adverse experiences assessed. Considering the instruments evaluated, two have a Brazilian Portuguese version available. 2) The adapted version of the Childhood Experiences International Questionnaire produced demonstrated to be of easy application and to comprehension, and obtained a good semantic equivalence when compared to the original version. Conclusion: Several instruments assessing the exposure to childhood adverse experiences have been used, assessing different parameters and dimensions, impairing the comparability of results. The provision of an international questionnaire adapted to the Brazilian context can contribute to the expansion and standardization of epidemiological research in Brazil. Its psychometric properties still have to be further evaluated.
Análise genética molecular para identificação de açaí e juçara em amostras comerciais por DNA barcoding e high resolution melting
(Universidade Federal do Espírito Santo, 2021-07-02) Lugon, Magda Delorence; Paneto, Greiciane Gaburro; https://orcid.org/0000000180354199; http://lattes.cnpq.br/8176374147579841; https://orcid.org/0000-0001-8156-7903; http://lattes.cnpq.br/0500101440332746; Ferreira, Marcia Flores da Silva; https://orcid.org/0000-0003-1541-6634; http://lattes.cnpq.br/5719813884063445; Ventura, José Aires; https://orcid.org/0000000314221739; http://lattes.cnpq.br/8687116881326074; Souza Filho, Gonçalo Apolinário de; https://orcid.org/0000-0003-1028-4425; http://lattes.cnpq.br/7935607913760531; Moura Neto, Rodrigo Soares de; https://orcid.org/0000-0002-4292-6878; http://lattes.cnpq.br/9827133223378136
Açaí is an Amazon fruit with antioxidant and anti-inflammatory properties used in the preparation of energy drinks consumed mainly in Brazil and lately exported to the whole world. It is obtained from two palm species, Euterpe oleracea and Euterpe precatoria. However, it may be mistaken with the fruit of a non-Amazon sister species (Euterpe edulis), called juçara, due to its morphological similarities. There is an increasing need for faster, more reliable, and reproducible methods that ensure all the ingredients included in a foodstuff, match the parameters claimed by the manufacturer or distributor in order to comply with regulations. Industrialized products can lose the original chemical and physical characteristics of their content. Even when these characteristics are preserved, the similarities between closely related species make their identification difficult. In recent years, DNA-based methods have contributed to guarantee the authenticity of food components and food products. DNA barcoding and High Resolution Melting (HRM) have been used with success in food safety. In this work, the main objective was to establish a DNA barcoding method to discriminate the three Euterpe species, and it was successfully applied to authenticate açaí commercial products sold in the Brazilian market. After testing nine regions as DNA barcoding candidates in reference samples, through conventional PCR and DNA sequencing, psbK-I region was elected for the authentication method. As result, 88.6% of the samples were classified as authenticated and 11.4% were classified as adulterated products. Authenticated açaí products showed clustered with E. oleracea reference plants. Four adulterated açaí products showed clustered with E. edulis. No products showed clustered with E. precatoria. Furthermore, the combination of two primers pairs, HRMpsbKI and HRMycf1b, in HRM technique was successfully useful to authenticate açaí products, enabling the identification of the species E. oleracea and E. precatoria, and differentiating the E. edulis. Admixtures of species E. edulis and E. oleracea were detected from 10% using HRMpsbKI primers. HRM was superior to DNA sequencing in authenticating samples. The HRM analysis presented higher resolution and cost effectiveness than DNA sequencing when authenticating commercial samples of açaí. These results bring us concern about the correct identification of species in food and about the occurrence of misleading advertising on labeled açaí products. Keywords: Euterpe. Authentication. Species. Products. psbK-I.
Análise genômica e transcriptômica de Saccharomyces cerevisiae em resposta a estresses consecutivos
(Universidade Federal do Espírito Santo, 2021-08-12) Costa, Ane Catarine Tosi; Fernandes, Patricia Machado Bueno; https://orcid.org/0000000326953638; http://lattes.cnpq.br/2441925791593067; https://orcid.org/0000000225219653; https://orcid.org/0000-0002-2521-9653; Brandão, Rogelio Lopes; https://orcid.org/0000-0002-8116-5979; http://lattes.cnpq.br/5985706469119679; Torres, Fernando Araripe Goncalves; https://orcid.org/0000-0002-3650-7271; http://lattes.cnpq.br/8228010543041248; Santos, Alexandre Martins Costa; https://orcid.org/0000000288018875; http://lattes.cnpq.br/4144105396879016; Ventura, José Aires; https://orcid.org/0000000314221739; http://lattes.cnpq.br/8687116881326074
During fermentation, yeasts face simultaneous and consecutive stresses, and their efficiency and performance depend on their adaptation to these unstable conditions. Even with the advent of omics analyzes, which allowed the complete yeast genome and its transcriptome to be studied, the response to consecutive stresses is still not well understood. To explore this, the genome and transcriptome of an industrial, stress-resistant strain (BT0510) was analyzed after consecutive stress and compared with other yeasts. Analysis of the genome of BT0510 identified several changes in genes involved in nitrogen metabolism and organelle integrity, as well as fragmentation of several flocculation genes. The strain also showed deletion of several genes encoding asparaginases, DUP240 family genes and maltose utilization loci. The common transcriptional response of BT0510 to different consecutive stresses indicated alterations in carbon metabolism, peroxisome activity, and oxidative stress response. Several genes were identified as key genes in the response, such as SYM1, STF2, and several HSPs along with the transcription factors ADR1 and USV1. Comparison of the transcriptome of BT0510 with a laboratory strain in response to the same stresses reinforced the role of ADR1 as well as SYM1 and several small HSPs. Comparative analysis of the transcriptome also suggested STF2 as a possible tolerance inducer in the industrial strain. Taken together, these results indicate target genes for the construction of more resistant strains that can optimize various fermentation processes.
APLICAÇÃO DE MODELOS ENERGÉTICOS DE TRANSPORTE DE SEDIMENTO NA AVALIAÇÃO DA VARIAÇÃO DA PROFUNDIDADE EM AMBIENTE COSTEIRO
(Universidade Federal do Espírito Santo, 2019-08-27) Jesus, Leonardo Carvalho de; Chacaltana, Julio Tomas Aquije; https://orcid.org/0000000324886232; http://lattes.cnpq.br/9108224414966705; https://orcid.org/; http://lattes.cnpq.br/; Buarque, Diogo Costa; https://orcid.org/000000032698520X; http://lattes.cnpq.br/8616432679482558; Moreira, Roger Matsumoto; https://orcid.org/; http://lattes.cnpq.br/; Carvalho, Nelson Violante de; https://orcid.org/; http://lattes.cnpq.br/; Reis, Jose Antonio Tosta dos; http://lattes.cnpq.br/7828468159099998
Calculation of sediment transport and seabed and coast evolution patterns are extremely complex due to the large number of physical variables involved both sediment transport and its resulting morphological changes. The sediment transport models for coast
Associação da metilação dos genes NR3C1 e BDNF com os níveis de glicose e resistência à insulina em adultos atendidos pelo SUS
(Universidade Federal do Espírito Santo, 2022-02-23) Souza, Marcele Lorentz Mattos de; Silva, Adriana Madeira Alvares da; https://orcid.org/0000000280780304; http://lattes.cnpq.br/6445492335035108; https://orcid.org/0000-0002-7364-8129; http://lattes.cnpq.br/8021072835101893; Guimarães, Marco Cesar Cunegundes; https://orcid.org/0000000321460180; http://lattes.cnpq.br/0261991057482057; Rocha, José Luiz Marques; https://orcid.org/0000000207835807; http://lattes.cnpq.br/7179771155975755; Errera, Flavia Imbroisi Valle; https://orcid.org/0000-0002-8069-6372; http://lattes.cnpq.br/9337327437538048; Arantes, Lidia Maria Rebolho Batista
High blood sugar and insulin resistance are high risk conditions for mortality and contribute to the development of type II diabetes mellitus (T2DM). Studies on epigenetic modifications related to NR3C1 gene methylation focus on psychosocial stress. There are no studies on the association between epigenetic changes in the NR3C1 gene and DM2, especially related to glucose levels and insulin resistance. However, studies have shown the association of brain-derived neurotrophic factor (BDNF) levels in T2DM patients. The present study aimed to analyze the relationship between glucose levels and insulin resistance with changes in NR3C1 and BDNF genes methylation levels in adult individuals. This study included 375 individual users of the Brazilian Public Unified Health System (SUS), aged 20-59 years, and evaluated socioeconomic status, lifestyle, anthropometric data, blood glucose, insulin resistance, and evaluation of NR3C1 and BDNF genes DNA methylation. Factors associated with glucose levels and insulin resistance were investigated using multivariate analysis GLzM with a significance of 5% (p<0,05). Our results showed that glucose levels and insulin resistance were directly related to age and NR3C1 gene methylation and indirectly related to overweight and obesity and tobacco consumption. Regarding the BDNF gene, our results showed a positive relationship between gene methylation and glucose levels and insulin resistance, while non-overweight and obesity were inversely related to glycemia and insulin resistance. Habits and lifestyle can alter gene regulation through DNA methylation, showing the complexity of environmental impacts on NR3C1 and BDNF genes methylation. These data contribute to a better understanding of the pathophysiology and diagnosis of metabolic diseases involving the NR3C1 and BDNF genes. Furthermore, associated risk factors must be taken into account in epigenetic studies as they directly interfere with blood glucose levels and insulin resistance.
Atuação de gradientes de radiação solar na fisiologia e bioquímica das plantas e na caracterização física dos frutos e na qualidade das sementes de dois genótipos de Theobroma cacao l. (Malvaceae)
(Universidade Federal do Espírito Santo, 2019-09-11) Seidel, Tatiane Aparecida Zorzal; Cuzzuol, Geraldo Rogerio Faustini; https://orcid.org/0000-0002-2055-492X; http://lattes.cnpq.br/6127436626143032; https://orcid.org/0000-0002-1970-0555; http://lattes.cnpq.br/4690823735316582; Silva, Diolina Moura; https://orcid.org/000000033885280X; http://lattes.cnpq.br/0341541450627705; Milanez, Camilla Rozindo Dias; https://orcid.org0000-0002-9516-2031; http://lattes.cnpq.br/1288447995978779; Gomes, Marcos Thiago Gaudio; https://orcid.org/; http://lattes.cnpq.br/9903805899337418; Arantes, Sara Dousseau; https://orcid.org/0000-0001-6202-4153; http://lattes.cnpq.br/6966978781439168
The cultivation of cacao (Theobroma cacao L.) in environments with little or no shade has gained prominence for increasing productivity in relation to cultivation in shaded environments. Cocoa is considered one of the most important perennial crops in the world because its seeds are the raw material for the production of chocolate, one of the most consumed foods in the world. However, studies with cacao plants exposed to full sun, study their physiological and biochemical behavior only when young, in their initial growth, there are no studies that evaluate the physiological and biochemical modifications of adult cacao plants, as well as the analysis of fruits and seeds formed under different conditions of solar radiation. In the present work, physiological and biochemical changes caused by different levels of solar radiation (100% full sun, 70%, 50% and 20%), in winter and summer, were evaluated in adult plants of two cacao genotypes. PH 16 and IPIRANGA 01, both resistant to witch's broom. It was also evaluated how the different levels of solar radiation (100% full sun, 70% and 50%) affect the physical characteristics of the fruits, as well as the seed quality. Plants of genotype PH 16 exhibited better performance under conditions of 100% solar radiation. The IPIRANGA 01 genotype showed behavioral variations, however such variations did not cause damage that prevented the development and maintenance of the plants, which allowed the adjustment and acclimation of the plants. Thus, both genotypes studied were able to acclimate to the different light levels studied. The fruits of the genotype PH 16, besides showing a higher yield of seeds and pulp when cultivated in full sun, also showed a higher yield, the seeds of this genotype in full sun exhibited characteristics favorable to the production of quality chocolates. The fruits of the IPIRANGA 01 genotype did not exhibit a higher yield in full sun when compared mainly to 50% of solar radiation, however in full sun the yield was higher than in the other treatments. Thus, full sun cultivation is indicated for the increase of cacao production and at the same time to obtain seed quality standards
Avaliação de citocinas e uso da espectroscopia FTIR como ferramenta na triagem do câncer de mama
(Universidade Federal do Espírito Santo, 2022-07-13) Faria, Rodrigo Alves; Gouvea, Sonia Alves; https://orcid.org/000000015180471X; http://lattes.cnpq.br/7268228122543743; https://orcid.org/0000-0002-1529-3817; http://lattes.cnpq.br/2836257154116274; Mauad, Helder; http://lattes.cnpq.br/4554702077415995; Rodrigues, Lívia Carla de Melo; http://lattes.cnpq.br/2084216553746326; Endlich, Patrick Wander; https://orcid.org/0000-0002-7597-3603; http://lattes.cnpq.br/9669721267985878; Silva, Adriana Madeira Alvares da; https://orcid.org/0000000280780304; http://lattes.cnpq.br/6445492335035108
Breast cancer is the most incident and the fifth in mortality worldwide, with a heterogeneous character, its spread involves a succession of clinical and pathological stages. There is an association between breast cancer and cardiovascular damage, recognized as a poor prognosis regardless of age, for this reason, the clinical approach using new tools that makes it possible to investigate the anticipated inflammatory profile, as well as improve the screening approach aimed at early diagnosis, are essential and necessary strategies, therefore, our aim was to investigate the inflammatory profile in women with breast cancer and apply FTIR spectroscopy as a screening method. We included 90 patients with an initial diagnosis of breast cancer. Clinical-epidemiological data were obtained together with blood collection before therapy. The present study showed that the increased levels of cytokines TNF-α, INF-γ, Il-2, IL-6, IL-17A, IL-4 and IL-10 by flow cytometry in the cancer, tumor size, Axillary lymph nodes and distant metastasis are associated with low overall survival and worse prognosis, as well as being more susceptible to the pathogenesis of several CVD's. Regarding FTIR spectroscopy, the method distinguished cancer and control samples by supervised analysis (PLS-DA). The main variance was found in the band 1511 cm-1 in the control group, 1502 and 1515 cm-1 in the cancer group. The spectral peaks responsible for the identification of breast cancer were attributed to proteins and amide II. Its spectral biomarker performed the distinction by plasma obtaining 97% sensitivity, 93% specificity, 97% ROC curve and 94% prediction. In light of the above, we suggest the clinical application of the cytokines evaluated as a primary phase biomarker in women newly diagnosed with breast cancer, regardless of demographic variables and tumor size, before undergoing any oncological treatment, due to their potential as a predictor of cardiovascular dysfunction and prognostic evaluation, as well as, we propose FTIR spectroscopy as a tool to aid in breast cancer screening.
Avaliação do efeito do cigarro na expressão gênica e proteica em carcinoma epidermoide de cavidade oral: relação do tabagismo com elementos responsivos de hipóxia e estresse oxidativo
(Universidade Federal do Espírito Santo, 2021-08-31) Oliveira, Mayara Mota de; Silva, Adriana Madeira Alvares da; https://orcid.org/0000000280780304; http://lattes.cnpq.br/6445492335035108; https://orcid.org/0000-0003-2735-9788; http://lattes.cnpq.br/5495329160438980; Nunes, Fabio Daumas; https://orcid.org/0000-0002-7785-6785; http://lattes.cnpq.br/4909755821591847; Boeloni, Jankerle Neves; https://orcid.org/0000000300496854; http://lattes.cnpq.br/7669632202047727; Paula, Renato Graciano de; https://orcid.org/0000-0002-6712-437X; http://lattes.cnpq.br/9954356596390106; Santos, Marcelo dos; http://lattes.cnpq.br/9871702190449067
Squamous cell carcinoma of the oral cavity (OSCC) is associated with high mortality rates and its main risk factor is smoking. In relation to tobacco, it is composed by more than 7000 substances including nicotine. Nicotine contribution to carcinogenesis is related to the activation of multiple signaling pathways that also regulate the progression, growth, and metastasis of tumors by stimulating nicotinic acetylcholine receptors (nAChRs). Nicotine exposure can simulate the effects of hypoxia, and promote up-regulation in the expression of pathway-related genes such as HIF-1α, VEGF-A, FIH, PHD3. In addition, the constituents of tobacco are responsible for the generation of reactive oxygen species (ROS), which disturb cell homeostasis and promote damage to DNA, RNA, lipids, and proteins. Among the antioxidant defense mechanisms for maintenance of homeostasis and DNA repair, a set of proteins that act to reduce oxidative stress are mobilized. Protein superoxide dismutase (SOD) is the main intracellular defense mechanism against oxidative reactions, and Apurine/apyrimidinic endonuclease/redox factor (APE-1/REF-1) acts at the base excision repair pathway. This study aimed to understand the role of nicotine and smoking, through cigarette extract (CSE), in the expression of genes and proteins in the hypoxia, oxidative stress, and repair pathways in cell lines of squamous cell carcinoma of the cavity oral (SCC-9) and oral keratinocytes with dysplasia (DOK), and their associations with the prognosis and survival of 137 patients with OSCC, smokers and non- smokers. Cigarette Smoke Extract (CSE) has been shown to have a greater impact on reducing cell migration in the DOK lineage, and mobilizes SOD-1 expression in concentration-dependent response, while APE-1/REF-1 show a different kind of regulation being the response time-dependent in SCC-9 cells. In vivo, smoking contributed to the strong expression of SOD-1, and its positive expression was significantly associated with tumor size, differentiation, in addition to being a protective factor for better disease-free survival. APE-1/REF-1 expression was associated with tumor size and disease-specific survival. Regarding nicotine exposure, SCC-9 demonstrates to be more responsive to cellular modulation and response to hypoxia and oxidative stress, with exhibiting on the increased expression of SOD-1, APE-1/REF-1, and HIF-1α. Together, our findings demonstrate that the degree of malignancy may be a variable related to the time of activation of cellular mechanisms of overall survival in response to ROS and hypoxia in smokers.
Avaliação dos transtornos depressivos na atenção primária à saúde: performance, percepção e conhecimento dos médicos
(Universidade Federal do Espírito Santo, 2023-07-31) Bruzeguini, Meirielli Vieira; Viana, Maria Carmen Moldes; http://lattes.cnpq.br/4338126917250074; http://lattes.cnpq.br/4338126917250074; https://orcid.org/0000-0001-5711-9537; http://lattes.cnpq.br/8569488273561796; Fontenelle, Leonardo Ferreira; https://orcid.org/0000-0003-4064-433X; http://lattes.cnpq.br/9234772336296638; Pang, Wang Yuan; https://orcid.org/0000-0001-7076-8312; http://lattes.cnpq.br/9846549859258950; Fortes, Sandra Lucia Correia Lima; https://orcid.org/0000-0002-9918-1555; http://lattes.cnpq.br/8632178826165568; Dalla, Marcello Dala Bernardina
Depressive disorders (TDs) are highly prevalent in all populations and often lead affected individuals to seek medical care. Primary Health Care (PHC) plays a key role as gate-access to health services, having an important function in the coordination and integration of mental health services. The objectives of this study were to carry out a review of the instruments more frequently used to identify and diagnose TDs, to evaluate the performance of the screening instrument K6 in the detection of psychological distress in the general population, and to investigate the perceptions and knowledge of general medical doctors about screening tools and mental health care in patients with TDs. Three original articles were produced. In the first article, we conducted an integrative review of the main instruments used in PHC to identify and diagnose TDs, describing 22 different instruments and their specific characteristics. In the second article, we demonstrated that K6 has good performance in identifying mood disorders, with high specificity and sensitivity (88.8% and 80.2%, respectively). In the third article, we analyzed the perceptions and knowledge of general medical doctors about the use of screening instruments in PHC and found that most physicians are unaware of such tools, and also, face a scenario of work overload and challenges in the mental health care network, which makes it difficult to implement new practices. PHC plays a strategic role in the identification, diagnosis, and early treatment of mental disorders, especially depressive disorders, due to their high prevalence. However, it is necessary to integrate improvements in the quality of care by reorganizing work processes, strengthening the care network, and training professionals in the identification and treatment of depressive disorders, as well as other common mental health in the general population.
Caracterização da resposta mediada por células T de memoria durante a leishmaniose cutânea e mucocutânea causada por Leishmania brasiliensis
(Universidade Federal do Espírito Santo, 2019-09-20) Martins, Regia Ferreira; Gomes, Daniel Claudio de Oliveira; https://orcid.org/; http://lattes.cnpq.br/3965075540969796; https://orcid.org/; http://lattes.cnpq.br/; Schuenck, Ricardo Pinto; https://orcid.org/0000000198255762; http://lattes.cnpq.br/1211608551542058; Giunchetti, Rodolfo Cordeiro; https://orcid.org/; http://lattes.cnpq.br/; Rodrigues, Rodrigo Ribeiro; https://orcid.org/000000020675110X; http://lattes.cnpq.br/3822046497362615; Zeidler, Sandra Lucia Ventorin Von; https://orcid.org/0000000288975747; http://lattes.cnpq.br/5785612863130498
Leishmaniasis is a chronic disease with different clinical forms, which depend on the parasite species and the host's immune response. Localized Cutaneous Leishamnasis (LCL) is the most common form found in the world. Due to the importance of T-cell-media
Caracterização química de extratos e óleos essenciais de aroeira (Schinus terebinthifolia Raddi) e avaliação das atividades anti-Helicobacter pylori e citotóxica contra linhagem celular de adenocarcinoma gástrico
(Universidade Federal do Espírito Santo, 2023-08-18) Gomes, Rodrigo Borges de Araujo; Kuster, Ricardo Machado; https://orcid.org/0000000289615348; http://lattes.cnpq.br/4149814906786366; https://orcid.org/0000-0001-5162-7725; http://lattes.cnpq.br/7953382988702353; Fortunato, Frederico da Silva; Cunha Neto, Alvaro; http://lattes.cnpq.br/7448379486432052; Kitagawa, Rodrigo Rezende; https://orcid.org/0000000222086699; http://lattes.cnpq.br/4424075292014459; Andreao, Almir
Brazilian peppertree (Schinus terebinthifolia Raddi) is a medicinal plant used in the treatment of some diseases and has several biological activities described in the literature. In this work, the chemical composition of essential oils and hydroethanolic extracts of leaves, fruits, bark and, residues from the pink pepper processing industry was carried out. The evaluation of anti-Helicobacter pylori and antiproliferative activities against gastric adenocarcinoma cell line (AGS) was also performed. The essential oils samples were analyzed by gas chromatography coupled to mass spectrometry (GC-MS) and the extracts by ESI (-) FT-ICR MS (Electrospray Ionization Fourier transform-ion cyclotron resonance mass spectrometry). The main components of the essential oils were the monoterpenes 3-carene, α-phelandrene, p-cymene, αpinene and limonene. The essential oil of leaves showed the highest content of sesquiterpenes, mainly caryophyllene and its oxide. All essential oils showed antimicrobial (MIC = 256 - 512 µg/mL) and antiproliferative activity with IC50 ranging from 68.64 to 109.50 µg/mL. In the extracts, flavonoids, gallotannins and triterpene acids were identified, mainly masticadienoic acid and schinol. The antiproliferative extracts were from leaves (IC50 = 42.41 ± 0.76 µg/mL), agroindustry residue (IC50 = 103.70 ± 0.67 µg/mL) and bark (IC50 = 143.40 ± 0.71 µg/ml). In these samples, tetra, penta and hexagalloylglucose were identified. They can be related to the observed cytotoxic effect. The extracts also showed anti-H. pylori activity with MIC between 256 and 1024 µg/mL and MBC between 512 and 1024 µg/mL. The extract from leaves was the most active. It was fractionated and the fractions subjected to biological assays. The ethyl acetate fraction was more active against AGS (IC50 = 21.43 µg/mL) and the aqueous fraction showed the highest activity against H. pylory (MIC = 128 µg/mL). Principal component analysis (PCA) was used to differenciate leaf extracts at different stages of development from infrared spectroscopy and mass spectrometry data. The PCA model applied to mass spectrometry data proved to be very efficient to discriminate groups of leaves at different stages of development, in addition to indicating a different tendency in the production of secondary metabolites by different genotypes of Schinus terebinthifolia. Methyl digallate, quinic acid hexoside, digallic acid and methyl gallate were the substances that most contributed to the differentiation of leaf stages. Infrared spectroscopy data were also efficient in separating groups related to developmental stages, mainly young leaves. It was also possible to discriminate one of the genotypes by the two techniques. The results of this work contribute to the knowledge about aroeira, exploring the possibility of its use, as well as the residues of the pink pepper processing industry, for the extraction of substances with biological potential. In addition, knowledge of the distribution of its metabolites guides the best stage of leaf development to prepare potentially active extracts.
CERVANTES APUD BORGES: “PRESCINDIR DO PAI À CONDIÇÃO DE SERVIR-SE DELE”
(Universidade Federal do Espírito Santo, 2019-07-01) Menezes, Luciana Pena Vila Lima de; Nascimento, Jorge Luiz Do; https://orcid.org/; http://lattes.cnpq.br/5314773566668629; https://orcid.org/; http://lattes.cnpq.br/; Neves, Antonio Carlos Felix das; https://orcid.org/; http://lattes.cnpq.br/; Oliveira, Ester Abreu Vieira de; https://orcid.org/; http://lattes.cnpq.br/3293718089972581; Amaral, Sergio da Fonseca; https://orcid.org/; http://lattes.cnpq.br/9383077540938356; Dutra, Paulo Roberto de Souza; http://lattes.cnpq.br/1256149380405075
abstract
Ciganos na mídia jornalística brasileira: uma análise a partir da perspectiva psicossocial da memória
(Universidade Federal do Espírito Santo, 2023-09-30) Cardoso, Grecy Kelle de Andrade; Bonomo, Mariana; http://lattes.cnpq.br/4087691008379051; https://orcid.org/0000-0002-6384-3545; Menandro, Maria Cristina Smith; http://lattes.cnpq.br/5351297661579846; Espindula, Daniel Henrique Pereira; Brasil, Julia Alves; Jardim, Adriano Pereira; http://lattes.cnpq.br/5421197565198625
The present thesis mainly aims to investigate the historical documentary memory about the social object 'Roma people', based on the analysis of journalistic pieces published in a reference Brazilian media, taking as a time frame the period between the year of promulgation of the Brazilian Federal Constitution (1988) and the year 2022. The theoretical support used was the conceptual field of the psychosocial perspective of Social Memory. To this end, descriptive and exploratory research was carried out, using a documentary approach through textual and iconic analysis of the content published in journalistic pieces by Jornal O Globo, considering 35 years of reference. The research was carried out in three complementary phases, with the same data source, but differentiated in terms of specific objectives and data processing and analysis methods, namely: 1). Phase 1, refers to the analysis of the textual content about the social object ‘Roma people’ in general. In this phase, 8752 journalistic pieces were used, which were analyzed using Category-thematic Content Analysis; 2). In phase 2, the aim was to identify the network of meanings associated with the term “Roma people”, through the analysis of textual production on the uses of this word in contexts that did not refer to Roma individuals and peoples. In order to analyze the data in this second phase, lexical analysis was carried out using Descending Hierarchical Classification (DHC) and Correspondence Factorial Analysis (CFA), processed using the IRAMUTEQ software, in a data corpus composed of 7691 journalistic pieces; and 3). In phase 3, in turn, the objective was to analyze journalistic pieces that specifically focused on Roma individuals and peoples, considering both the textual content of 1061 journalistic pieces and the iconic content of 80 images presented in the publications. In the third phase, lexical analysis was carried out using DHC and content analysis of the textual corpus, as well as Semiotic Analysis of the images in the corpus formed by the images. In addition to the adjectives used to characterize Roma people, the results found in the first phase 12 allowed us to identify eight main themes, namely: anti-gypsyism (anti-Roma) and violence; places marked by the presence of Roma people; political dimension; Roma people and ethnicities; the word ‘gypsy’ (Roma); mystical and religious practices; products and services provided; and artistic productions and commemorative events. In the second phase, the results demonstrated the presence of stereotypical content associated with the term ‘gypsies’, which especially highlighted the mystical and artistic dimensions related to this term. In the third phase, the results indicated differences between Roma in the international and national context, as well as discriminatory practices, anti-Roma and violence of different kinds, in addition to nomadism, mysticism, traditions and the artistic legacy associated to them. From the integrated analysis of the results, it was possible to discuss the different stereotypes directed at Roma people by the journalistic media and reflect on the effects of the processes of social invisibility experienced by the Roma ethnic minority, which is still under the shadow of prejudice and social discrimination, in Brazil and around the world. Carrying out this study also allowed us to reflect on the dynamics of dispute between the memorable and the forgotten, as a power game, present in the process of constructing a version of historical memory about the Roma people.
COMPOSTOS ORGÂNICOS VOLÁTEIS PRECURSORES DE OZÔNIO (HIDROCARBONETOS E CARBONILAS): ANÁLISE DO POTENCIAL DE FORMAÇÃO DE OZÔNIO E EFEITOS À SAÚDE EM ÁREA URBANA
(Universidade Federal do Espírito Santo, 2022-09-21) Alves, Mayana Rigo; Junior, Neyval Costa Reis; https://orcid.org/0000000261594063; http://lattes.cnpq.br/4944106074149720; https://orcid.org/; http://lattes.cnpq.br/; Andrade, Maria de Fatima; https://orcid.org/; http://lattes.cnpq.br/; Santos, Jane Meri; https://orcid.org/0000000339332849; http://lattes.cnpq.br/0120226021957540; Goulart, Elisa Valentim; https://orcid.org/0000000200510778; http://lattes.cnpq.br/0014236670973457; Nogueira, Thiago; Galvao, Elson Silva
abstract
Comunicação verbal e não-verbal: um olhar sobre as expressões faciais de emoção em tradutores intérpretes de língua de sinais-português
(Universidade Federal do Espírito Santo, 2023-08-25) Guilherme, Rafael Silva; Tokumaru, Rosana Suemi; https://orcid.org/0000-0003-2859-4114; http://lattes.cnpq.br/4294698135718928; https://orcid.org/0000-0003-4720-1929; http://lattes.cnpq.br/3858305541884141; Menandro, Maria Cristina Smith; https://orcid.org/0000-0003-4339-2975; http://lattes.cnpq.br/5351297661579846; Ferrari, Ana Carolina Machado; https://orcid.org/0000-0002-9820-2799; http://lattes.cnpq.br/3733548420359886; Santos, Hadassa Rodrigues; https://orcid.org/0000-0002-4982-3425; http://lattes.cnpq.br/2476840946366296
Facial expressions of emotion (FEE) such as joy, sadness, anger, disgust, fear, surprise, and the neutral face (Ekman & Friesen, 1976) can be characterized as part of nonverbal communication. They are spontaneous, universal, non-symbolic expressions produced and recognized by individuals who communicate through both oral and sign languages (LS). These expressions form part of the grammar of LS and are considered Non-Manual Markers. The Sign Language and Portuguese Interpreter - TILSP is the professional who communicates through LS. In their formal training, TILSPs learn specific language competencies and skills, and learning and training in facial expressions are necessary for their development in the interpretation and translation process. The overall objective of this thesis was to investigate the influence of learning and experience with sign language on the recognition and display of facial expressions of emotion by sign language interpreters. Four independent studies were proposed. The first article conducted a scoping review of studies on FEE and LS. The results indicate that most studies were conducted with deaf signers compared to individuals without knowledge of sign language, and no significant differences were found between the groups. The second article investigated whether learning sign language could influence the recognition of FEE in TILSPs using digital avatar images with human faces. The results suggest that professionals did not show better accuracy in recognizing FEE. However, as expected, images with male faces and higher intensity were statistically more recognized than those with lower intensity and female faces. In the third article, the same method used in the previous study was replicated, but static (photographs) and dynamic (videos) images were added. This study investigated whether learning sign language could influence the recognition of FEE. The results suggest that professionals performed better in various facial recognition tasks, being faster and reporting fewer difficulties. Regarding stimuli, images with the avatar's face were more recognized than others. The fourth study aimed to investigate the influence of learning or experience in Brazilian Sign Language (Libras) on the production of FEE in sign language interpreters. The results indicate that, overall, learning sign language did not have a significant impact on the production of emotions. The studies presented allow us to understand that learning sign language can indeed influence the recognition of FEE in hearing individuals studying or working in sign language translation and interpretation. However, this recognition may not occur for all emotions. On the other hand, in relation to the production of FEE, our findings do not support the same influence. The results of this thesis can contribute to the training of TILSPs, including studies on FEE, and encourage future research in the field, expanding discussions on emotional expressions in sign language communication.
Consumo de bebidas e desfechos cardiometabólicos: resultados do ELSA-Brasil
(Universidade Federal do Espírito Santo, 2022-02-22) Siqueira, Jordana Herzog; Molina, Maria Del Carmen Bisi; https://orcid.org/0000-0002-8614-988X; http://lattes.cnpq.br/9238370951122705; https://orcid.org/0000-0003-0116-7411; http://lattes.cnpq.br/4953953665582972; Mill, José Geraldo; https://orcid.org/000000020987368X; http://lattes.cnpq.br/2497419234600362; Meireles, Adriana Lúcia; https://orcid.org/0000-0002-1447-953X; http://lattes.cnpq.br/5415462090135377; Diniz, Maria de Fátima Haueisen Sander; http://lattes.cnpq.br/4536552263207019; Oliveira, Elizabete Regina Araujo de; http://lattes.cnpq.br/4671078095444887
Consumption of alcoholic and non-alcoholic beverages is common in many societies and their levels of consumption are associated with the occurrence of chronic diseases. In this regard, it is important to investigate the sociodemographic and health profile of consumers of these beverages to support effective public policies. In addition, there are gaps in the literature on the long-term effects of sugary and unsweetened beverage consumption on cardiometabolic health, especially in populations from low- and middle-income countries, which are undergoing rapid nutritional transition. Thus, the aim was to study the consumption of alcoholic and non-alcoholic beverages according to sociodemographic, health, and geographic location data, and to investigate, prospectively, the relationship between the consumption of sugar-sweetened soft drinks and unsweetened fruit juice and cardiometabolic outcomes in participants of the Longitudinal Study of Adult Health (ELSA-Brasil). ELSA-Brasil is a multicentric cohort composed of 15,105 active or retired public servants of both sexes, aged 35 to 74 years, from six public higher education and research institutions (USP, UFMG, UFBA, UFRGS, UFES and Fiocruz). Baseline (2008-2010) and the second evaluation (2012-2014) data were used. Sociodemographic data, life and health habits, medical history, and medication use were collected through a structured questionnaire, in interviews during visits to the research centers. Food consumption was assessed at baseline using a validated food frequency questionnaire. The cumulative incidence of outcomes (hyperuricemia [≥7.0 mg/dL for men and ≥5.7 mg/dL for women] and metabolic syndrome [Joint Interim Statement]) was evaluated after 4 years of follow-up. The results were described in three original articles. The first manuscript aimed to describe the consumption of alcoholic and non-alcoholic beverages at baseline, according to sociodemographic, health, and location variables. It was observed that 8% of the total caloric value came from non-alcoholic beverages (5.6% = sugary drinks), and 4% from alcoholic beverages (2.7% = beer). Men reported higher consumption of alcoholic beverages, and women, higher consumption of non-alcoholic beverages. Consumers of unsweetened and artificially sweetened beverages reported moderate/strong physical activity, were former smokers, and had a higher education. The opposite was found for sugary drinks. Eutrophic people reported higher consumption of sugary beverages and those obese, artificially sweetened beverages and beer. The consumption of alcoholic beverages varied with age (youth: beer; elderly: wine/spirits) and education (low education: beer/spirits; higher education: wine). Coffee, fruit juice, and sugar-sweetened soft drinks were the most consumed non-alcoholic beverages and beer was the most prevalent alcoholic beverage. Consumption variation was observed according to geographic location. The second and third manuscripts prospectively evaluated the relationship between the consumption of sugar-sweetened soft drinks, unsweetened fruit juice, and cardiometabolic outcomes (hyperuricemia and metabolic syndrome, respectively). After 4 years of follow-up, regardless of potentially confounding variables, higher sugar-sweetened soft drinks consumption (men: 401 ± 303 mL/day; women: 390 ± 290 mL/day) increased the relative risk of hyperuricemia by 30% (men) and 40 % (women), and was associated with a mean increase in serum uric acid levels (men: β = 0.14 mg/dL; 95%CI = 0.41-0.24; women: β = 0.11 mg/dL; 95%CI = 0.00-0.21). Higher sugar-sweetened soft drinks consumption (≥1 serving/day = 250 mL/day) increased the relative risk of metabolic syndrome (RR = 1.22; 95%CI = 1.04-1.45), elevated fasting glucose (RR = 1.23; 95%CI = 1.01-1.48), and high blood pressure (RR = 1.23; 95%CI = 1.00-1.54). Moderate consumption of this beverage (0.4 to <1 serving/day) increased the relative risk of high waist circumference (RR = 1.21; 95%CI = 1.02-1.42). After 4 years of follow-up, consumption of unsweetened fruit juice was not associated with hyperuricemia and metabolic syndrome and its components. It is concluded that there is an important caloric share of alcoholic and non-alcoholic beverages in the diet of ELSA-Brasil participants and the association of consumption of these beverages with sociodemographic, lifestyle, and location data. Individuals who reported higher consumption of sugar-sweetened soft drinks had worse lifestyle habits and health conditions, and the opposite profile was observed for those who reported higher consumption of unsweetened fruit juice. No prospective association was observed between consumption of unsweetened fruit juice and cardiometabolic outcomes. Higher sugar-sweetened soft drinks consumption was associated with the incidence of hyperuricemia and metabolic syndrome, in a cohort of Brazilian adult and elderly public servants.
Crenças e atitudes sobre atendimentos em grupo na Atenção Básica à Saúde, no município de Vitória-ES.
(Universidade Federal do Espírito Santo, 2019-02-27) Velez, Yushiara Emily Vargas; Avellar, Luziane Zacche; https://orcid.org/000-0002-1878-7708; http://lattes.cnpq.br/8948015493681619; https://orcid.org/0000-0003-4918-0885; http://lattes.cnpq.br/1568940595297750; Menandro, Maria Cristina Smith; https://orcid.org/0000-0003-4339-2975; http://lattes.cnpq.br/5351297661579846; Menandro, Paulo Rogerio Meira; https://orcid.org/0000-0003-3095-4959; http://lattes.cnpq.br/2651570325312338; Coutinho, Sabrine Mantuan dos Santos; https://orcid.org/0000-0003-3939-6594; http://lattes.cnpq.br/7440436610120709; Saquetto, Diemerson
The aim of this thesis was to explore the attitudes and beliefs about group health in Primary Health Care constructed by participating users and those who do not participate in a group, and the possible significant associations between beliefs and attitudes and participation conditions. Three studies were performed, which allowed, for the thesis as a whole, the adoption of a mixed method with approach of methodological triangulation. The first two studies were done according to the qualitative approach and the third, quantitative. The first study presents the results obtained through semi-structured interviews with twenty users of both sexes who participated in group, analyzed through the Thematic Content Analysis. 54 themes and 4 categories emerged: 1) Perceptions about characteristics and functions of health group services; 2) Perceptions about results of the health group services; 3) Perceptions about difficulties related to health group services; and 4) Senses attributed to the health group services by family members, according to users. It was observed that the health practices, in the health group services, according to the users' beliefs and attitudes, are still centered on the traditional biomedical paradigm and the unilateral transmission of information, putting the professionals as only bearers of legitimate knowledge. The second study presented results obtained through semi-structured interviews with twenty users of both sexes who did not participate in a group, analyzed through the Thematic Content Analysis. Seventy themes and four categories were identified: 1) Beliefs about characteristics and functions of the health group services; 2) Beliefs about the conditions to participate in the health group services; 3) Beliefs about the negative aspects of the health group services and 4) Beliefs about the relationships between the health group services and the health system. It was observed that the users classified the groups as informative, as spaces to create bonds of friendship, of companionship, as space to generate income and work. Reported that the groups are destined for a specific public, with some disease, for poor communities and unemployed people; that to participate in these groups, they would need an invitation or present some specific problem of health. The groups were seen as "lessons." Discusses that these beliefs can be obstacles to the implementation of the health group services on Primary Health Care. The third study presents results obtained through a questionnaire based on a Likert-type scale with 187 users of both sexes, the data obtained were tabulated and processed using the SPSS software and the relations among the variables were identified with t test independent samples, Pearson correlation coefficient and hierarchical regression analysis. It was verified that the attitudes towards the groups were positive, that the users that participate of the groups manifest interest of continuing participating in the groups, which is not the case of those who do not participate. The latter group has shown itself less to disagree with negative attitudes and to adopt beliefs that can arise as obstacles for groups. The results reinforce the need to work with inadequate beliefs and the perception of difficulties in order to increase the chance of participation and the pertinence of the groups to Primary Health Care
DA VULNERABILIDADE À RESILIÊNCIA: Autonomismo, invisibilidade e microdesastre em Vila Velha — ES
(Universidade Federal do Espírito Santo, 2022-04-29) Junior, Edilson Cavalcante de Oliveira; Mendonca, Eneida Maria Souza; https://orcid.org/; http://lattes.cnpq.br/0761476745619922; https://orcid.org/; http://lattes.cnpq.br/; Gomes, Edvania Torres Aguiar; https://orcid.org/0000-0002-0865-4805; http://lattes.cnpq.br/2073947620231592; Coelho, Andre Luiz Nascentes; https://orcid.org/0000-0001-9068-495X; http://lattes.cnpq.br/7506224671150309; Miranda, Clara Luiza; https://orcid.org/; http://lattes.cnpq.br/9723975125785156; Valencio, Norma Felicidade Lopes da Silva; https://orcid.org/0000-0003-1855-3458; http://lattes.cnpq.br/7161606146208875
This thesis analyzes the impacts resulting from floods and inundations in spaces under conditions of socio-environmental vulnerability and the local mitigation practices. It is a recurring scenario related to climatic issues typical of tropical urban environments in so-called “developing” countries, aggravated by political, social and economic issues. Efforts seasonally undertaken to mitigate hydrological disasters shows incipient results, which involve the public, private and third sector. The recurrence of this situation, especially in spaces not lit by the media or the government, results in the adoption of autonomous practices conducted by directly affected social agents, who, in an associative manner, plan and act in reducing the risk of disaster improvised and on their own, using embankments, construction of dikes and barriers, suspension of structures and pumping liquids, which appear as palliatives against the hydrological complexity of the entire city area. This thesis includes theoretical and empirical reviews based on a case study, in the face of disaster threats, exposing measures of resistance, transformation and resilience. In this sense, research was carried out in a part of the city of Vila Velha, Espírito Santo, Brazil, particularly in the Dom João Batista neighborhood because of its historical, environmental and social characteristics. Located on the margins of the Aribiri River, it emerged from irregular occupations and its inhabitants live in a vulnerable situation. Starting from the systemic analysis and the hypothetical-deductive method, readings and bibliographic, documentary, reports, news, iconographic records and satellite images were carried out. Among the most important analyzes is the Municipal Plan for Disaster Risk Reduction. The research also includes an analytical treatment of the data obtained through field visits and unstructured interviews with social agents. Among the results achieved in this research is the discussion of the need to give greater visibility to the praxis carried out at the microscale, in the spatial areas of greater vulnerability, which experience a condition of multi-threats in their fixation resistances reinforced by the invisibility in the sphere of urban planning.

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